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Panama Canal cruise
Panama Canal cruise

Los Angeles Cruise Guide > Destinations > Panama Canal

Panama Canal Cruise from Los Angeles

The Panama Canal is one of the marvels of the world, and you can experience it for yourself on a cruise out of LA. Six cruise lines offer cruises through the canal. Most are one-way but some are round-trip. See the full calendar of departures below.

The Panama Canal is 100 years old and was recently expanded, so this is a good time to go see it.

One-Way Panama Canal Cruises from LA

Many one-way cruises to the Panama Canal are available out of Los Angeles. Most end in Florida, but a few go to New York. These cruises make a full transit of the canal and visit ports in the Caribbean too.

15-day Panama Canal cruise on Princess Cruises. One-way from LA to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), San Juan del Sur (Nicargua), Puntarenas (Costa Rica), the Panama Canal, Cartagena (Colombia), and Aruba.
• 2017 departure: December 6.

14-day Panama Canal cruise on Norwegian Cruise Line. One-way from LA to Miami (Florida). Visit Cabo San Lucas (Mexico), Acapulco (Mexico), Puerto Quetzal (Guatemala), San Juan del Sur (Nicaragua), Puntarenas (Costa Rica) and Cartagena (Colombia).
• 2018 departure: January 5.

15-day Panama Canal cruise on Princess Cruises. One-way from LA to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), San Juan del Sur (Nicargua), Puntarenas (Costa Rica), the Panama Canal, Cartagena (Colombia) and Aruba.
• 2018 departure: January 5.

15-day Panama Canal cruise on Princess Cruises. One-way from LA to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), San Juan del Sur (Nicargua), Puntarenas (Costa Rica), the Panama Canal, Cartagena (Colombia) and Aruba.
• 2018 departure: January 9.

14-day Panama Canal cruise on Norwegian Cruise Line. One-way from LA to Miami (Florida). Visit Cabo San Lucas (Mexico), Acapulco (Mexico), Puerto Quetzal (Guatemala), San Juan del Sur (Nicaragua), Puntarenas (Costa Rica) and Cartagena (Colombia).
• 2018 departure: February 2.

15-day Panama Canal cruise on Princess Cruises. One-way from LA to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), San Juan del Sur (Nicargua), Puntarenas (Costa Rica), the Panama Canal, Cartagena (Colombia) and Aruba.
• 2018 departure: February 4.

16-day Panama Canal cruise on Oceania Cruises. One-way from LA to Miami (Florida). Visit San Diego (California), Cabo San Lucas (Mexico), Acapulco (Mexico), Puerto Quetzal (Guatemala), San Juan Del Sur (Nicaragua), Puntarenas (Costa Rica), the Panama Canal, Cartagena (Colombia) and George Town (Cayman Islands).
• 2018 departure: April 6.

14-day Panama Canal cruise on Norwegian Cruise Line. One-way from LA to Miami (Florida). Visit Cabo San Lucas (Mexico), Acapulco (Mexico), San Juan del Sur (Nicaragua), Puntarenas (Costa Rica), Cartagena (Colombia) and Grand Cayman (Cayman Islands).
• 2018 departure: April 8.

17-day Panama Canal cruise on Princess Cruises. One-way from LA to Fort Lauderdale (Florida). Visit Cabo San Lucas (Mexico), San Juan del Sur (Nicargua), Puntarenas (Costa Rica), the Panama Canal, Santa Marta (Colombia) and Aruba.
• 2018 departure: May 14.

16-day Panama Canal cruise on Oceania Cruises. One-way from LA to Miami (Florida). Visit San Diego (California), Cabo San Lucas (Mexico), Acapulco (Mexico), Puerto Quetzal (Guatemala), Corinto (Nicaragua), Puntarenas (Costa Rica), the Panama Canal, Cartagena (Colombia) and George Town (Cayman Islands).
• 2018 departure: June 15.

15-day Panama Canal cruise on Princess Cruises. One-way from LA to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), San Juan del Sur (Nicargua), Puntarenas (Costa Rica), the Panama Canal, Cartagena (Colombia) and Aruba.
• 2018 departure: September 26.

15-day Panama Canal cruise on Norwegian Cruise Line. One-way from LA to Tampa (Florida). Visit Cabo San Lucas (Mexico), Acapulco (Mexico), Puerto Quetzal (Guatemal), San Juan del Sur (Nicaragua), Puntarenas (Costa Rica), Cartagena (Colombia) and Grand Cayman (Cayman Islands).
• 2018 departure: October 20.

14-day Panama Canal cruise on Norwegian Cruise Line. One-way from LA to Miami (Florida). Visit Cabo San Lucas (Mexico), Acapulco (Mexico), Puerto Quetzal (Guatemal), San Juan del Sur (Nicaragua), Puntarenas (Costa Rica) and Cartagena (Colombia).
• 2018 departure: November 2.

14-day Panama Canal cruise on Norwegian Cruise Line. One-way from LA to Miami (Florida). Visit Puerto Vallarta (Mexico), Manzanillo (Mexico), Puerto Quetzal (Guatemala), Puntarenas (Costa Rica) and Cartagena (Colombia).
• 2018 departure: November 3.

16-night Panama Canal cruise on Royal Caribbean. One-way from LA to New Orleans. Visit San Diego (California), Cabo San Lucas (Mexico), Puerto Vallarta (Mexico), Puerto Quetzal (Guatemala), Puntarenas (Costa Rica), Panama Canal, Colon (Panama) and Cartagena (Colombia).
• 2018 departure: November 29.

15-day Panama Canal cruise on Princess Cruises. One-way from LA to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), San Juan del Sur (Nicargua), Puntarenas (Costa Rica), the Panama Canal, Cartagena (Colombia) and Aruba.
• 2018 departure: December 7.

15-day Panama Canal cruise on Holland America Line. One-way from LA to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), Puerto Chiapas (Mexico), Puerto Quetzal (Guatemala), Corinto (Nicaragua), Puerto Caldera (Costa Rica), Panama Canal and Cartagena (Colombia).
• 2019 departure: January 7.

17-night Panama Canal cruise on Azamara. One-way from LA to Miami (Florida). Visit Cabo San Lucas (Mexico), Huatulco (Mexico), Puerto Chiapas (Mexico), Puerto Quetzal (Guatemala), San Juan del Sur (Nicaragua), Puntarenas (Costa Rica), the Panama Canal and Cartagena (Colombia).
• 2019 departure: February 22.

Round-Trip Panama Canal Cruises from LA

Roundtrip cruises to the Panama Canal out of Los Angeles are much rarer than one-way journeys. These cruises do not go all the way through the canal; instead they go half-way in and make a "partial transit".

19-day Panama Canal Holiday cruise on Princess Cruises. Round-trip from LA to Puerto Vallarta (Mexico), Huatulco (Mexico), Puerto Chiapas (Mexico), Puerto Quetzal (Guatemala), the Panama Canal, Puntarenas (Costa Rica), San Juan del Sur (Nicaragua), and Manzillo (Mexico).
• 2017 departure: December 21.

19-day Panama Canal cruise on Princess Cruises. Round-trip from LA to Huatulco (Mexico), Puerto Chiapas (Mexico), Puerto Quetzal (Guatemala), the Panama Canal, Puntarenas (Costa Rica), San Juan del Sur (Nicaragua) and Manzanillo (Mexico).
• 2018 departure: April 9.

19-day Panama Canal cruise on Princess Cruises. Round-trip from LA to Huatulco (Mexico), Puerto Chiapas (Mexico), Puerto Quetzal (Guatemala), the Panama Canal, Puntarenas (Costa Rica), San Juan del Sur (Nicaragua) and Manzanillo (Mexico).
• 2018 departure: November 18.

19-day Panama Canal cruise on Princess Cruises. Round-trip from LA to Huatulco (Mexico), Puerto Chiapas (Mexico), Puerto Quetzal (Guatemala), the Panama Canal, Puntarenas (Costa Rica), San Juan del Sur (Nicaragua) and Manzanillo (Mexico).
• 2019 departure: March 17.

Have fun. Explore the world. Take a cruise to the Panama Canal from Los Angeles.

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