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Panama Canal cruise
Panama Canal cruise

Los Angeles Cruise Guide > Destinations > Panama Canal

Panama Canal Cruises from Los Angeles

The Panama Canal is one of the marvels of the world, and you can experience it for yourself on a cruise out of LA. Six cruise lines offer cruises through the canal. Most are one-way to Florida or New York, but some are round-trip. See the full calendar of departures below.

The Panama Canal is 100 years old and was recently expanded, so this is a good time to go see it.

One-Way

14-day Panama Canal cruise on Norwegian Cruise Line. One-way from LA to Miami (Florida). Visit Cabo San Lucas (Mexico), Acapulco (Mexico), Puerto Quetzal (Guatemal), San Juan del Sur (Nicaragua), Puntarenas (Costa Rica) and Cartagena (Colombia).
• 2018 departure: November 2.

14-day Panama Canal cruise on Norwegian Cruise Line. One-way from LA to Miami (Florida). Visit Puerto Vallarta (Mexico), Manzanillo (Mexico), Puerto Quetzal (Guatemala), Puntarenas (Costa Rica) and Cartagena (Colombia).
• 2018 departure: November 3.

16-night Panama Canal cruise on Royal Caribbean. One-way from LA to New Orleans. Visit San Diego (California), Cabo San Lucas (Mexico), Puerto Vallarta (Mexico), Puerto Quetzal (Guatemala), Puntarenas (Costa Rica), Panama Canal, Colon (Panama) and Cartagena (Colombia).
• 2018 departure: November 29.

15-day Panama Canal cruise on Princess Cruises. One-way from LA to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), San Juan del Sur (Nicargua), Puntarenas (Costa Rica), the Panama Canal, Cartagena (Colombia) and Aruba.
• 2018 departure: December 7.

14-day Panama Canal cruise on Norwegian Cruise Line. One-way from Los Angeles to Miami (Florida). Visit Cabo San Lucas (Mexico), Acapulco (Mexico), Puerto Quetzal (Guatemala), San Juan del Sur (Nicaragua), Puntarenas (Costa Rica) and Cartagena (Colombia).
• 2019 departure: January 4.

15-day Panama Canal cruise on Holland America Line. One-way from LA to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), Puerto Chiapas (Mexico), Puerto Quetzal (Guatemala), Corinto (Nicaragua), Puerto Caldera (Costa Rica), Panama Canal and Cartagena (Colombia).
• 2019 departure: January 7.

19-day Panama Canal cruise on Norwegian Cruise Line. One-way from Los Angeles to New York. Visit Cabo San Lucas (Mexico), Puerto Vallarta (Mexico), Ixtapa (Mexico), Puerto Quetzal (Guatemala), Corinto (Nicaragua), Puntarenas (Costa Rica), Cartagena (Colombia), Santa Marta (Colombia), Aruba, Curacao and Bonaire.
• 2019 departure: January 27.

14-day Panama Canal cruise on Norwegian Cruise Line. One-way from Los Angeles to Miami (Florida). Visit Cabo San Lucas (Mexico), Acapulco (Mexico), Puerto Quetzal (Guatemala), San Juan del Sur (Nicaragua), Puntarenas (Costa Rica) and Cartagena (Colombia).
• 2019 departure: February 1.

17-night Panama Canal cruise on Azamara. One-way from LA to Miami (Florida). Visit Cabo San Lucas (Mexico), Huatulco (Mexico), Puerto Chiapas (Mexico), Puerto Quetzal (Guatemala), San Juan del Sur (Nicaragua), Puntarenas (Costa Rica), the Panama Canal and Cartagena (Colombia).
• 2019 departure: February 22.

14-day Panama Canal cruise on Norwegian Cruise Line. One-way from Los Angeles to Miami (Florida). Visit Cabo San Lucas (Mexico), Acapulco (Mexico), Puerto Quetzal (Guatemala), San Juan del Sur (Nicaragua), Puntarenas (Costa Rica) and Cartagena (Colombia).
• 2019 departure: March 30.

16-night Panama Canal cruise on Cunard Line. One-way from Los Angeles to Fort Lauderdale (Florida). Visit Cabo San Lucas (Mexico), Puerto Quetzal (Guatemala), Puntarenas (Costa Rica), Fuerte Amador (Panama), the Panama Canal and Aruba.
• 2019 departure: July 5.

15-day Panama Canal cruise on Princess Cruises. One-way from Los Angeles to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), San Juan del Sur (Nicargua), Puntarenas (Costa Rica), Fuerte Amador (Panama), the Panama Canal (new locks) and Cartagena (Colombia).
• 2019 departure: September 22.

15-night Panama Canal cruise on Regent Seven Seas. One-way from Los Angeles to Miami (Florida). Visit Ensenada (Mexico), Cabo San Lucas (Mexico), Zihuatanejo (Mexico), Acajutla (El Salvador), San Juan del Sur (Nicaragua), Puntarenas (Costa Rica), the Panama Canal (daylight transit) and Cartagena (Colombia).
• 2019 departure: September 30.

15-day Panama Canal cruise on Carnival Cruise Line. One-way from Long Beach to Tampa (Florida). Visit Cabo San Lucas (Mexico), Puerto Quetzal (Guatemala), Puntarenas (Costa Rica), Panama Canal, Cartagena (Colombia), Santa Marta (Colombia) and Grand Cayman (Cayman Islands).
• 2019 departures: October 12.

19-day Panama Canal cruise on Seabourn. One-way from Los Angeles to Miami (Florida). Visit Cabo San Lucas (Mexico), Huatulco (Mexico), Puerto Chiapas (Mexico), Puerto Quetzal (Guatemala), Puntarenas (Costa Rica), the Panama Canal, Colon (Panama), Cartagena (Colombia) and Port Antonio (Jamaica).
• 2019 departure: October 16.

15-day Panama Canal cruise on Princess Cruises. One-way from Los Angeles to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), San Juan del Sur (Nicargua), Puntarenas (Costa Rica), Fuerte Amador (Panama), the Panama Canal (new locks) and Cartagena (Colombia).
• 2019 departure: October 18.

16-night Panama Canal cruise on Royal Caribbean. One-way from Los Angeles to Fort Lauderdale (Florida). Visit Cabo San Lucas (Mexico), Puerto Vallarta (Mexico), Puerto Quetzal (Guatemala), Puntarenas (Costa Rica), the Panama Canal, Colon (Panama), Cartagena (Colombia) and Grand Cayman (Cayman Islands).
• 2019 departure: October 30.

21-day Panama Canal cruise on Norwegian Cruise Line. One-way from Los Angeles to New York. Visit Cabo San Lucas (Mexico), Mazatlan (Mexico), Puerto Vallarta (Mexico), Puerto Quetzal (Guatemala), Puntarenas (Costa Rica), Cartagena (Colombia), Santa Marta (Colombia), Aruba, Curacao and St Maarten.
• 2019 departure: November 3.

15-night Panama Canal cruise on Royal Caribbean. One-way from Los Angeles to San Juan (Puerto Rico). Visit Cabo San Lucas (Mexico), Puerto Vallarta (Mexico), Puerto Quetzal (Guatemala), Puntarenas (Costa Rica), the Panama Canal, Cartagena (Colombia) and Aruba.
• 2019 departure: December 1.

15-day Panama Canal cruise on Princess Cruises. One-way from Los Angeles to Fort Lauderdale (Florida). Visit Puerto Vallarta (Mexico), Huatulco (Mexico), San Juan del Sur (Nicargua), Puntarenas (Costa Rica), Fuerte Amador (Panama), the Panama Canal (new locks) and Cartagena (Colombia).
• 2019 departure: December 3.

16-day Panama Canal cruise on Oceania Cruises. One-way from Los Angeles to Miami (Florida). Visit Catalina Island (California), Cabo San Lucas (Mexico), Acapulco (Mexico), Puerto Quetzal (Guatemala), San Juan del Sur (Nicaragua), Puntarenas (Costa Rica), the Panama Canal, Cartagena (Colombia) and Grand Cayman (Cayman Islands).
• 2019 departure: December 21.

Round-Trip

Roundtrip cruises to the Panama Canal out of Los Angeles are much rarer than one-way journeys. These cruises do not go all the way through the canal; instead they go half-way in and make a "partial transit".

19-day Panama Canal cruise on Princess Cruises. Round-trip from LA to Huatulco (Mexico), Puerto Chiapas (Mexico), Puerto Quetzal (Guatemala), the Panama Canal, Puntarenas (Costa Rica), San Juan del Sur (Nicaragua) and Manzanillo (Mexico).
• 2018 departure: November 18.

19-day Panama Canal cruise on Princess Cruises. Round-trip from LA to Huatulco (Mexico), Puerto Chiapas (Mexico), Puerto Quetzal (Guatemala), the Panama Canal, Puntarenas (Costa Rica), San Juan del Sur (Nicaragua) and Manzanillo (Mexico).
• 2019 departure: March 17.

19-day Panama Canal cruise on Princess Cruises. Round-trip from Los Angeles to Huatulco (Mexico), Puerto Chiapas (Mexico), Puerto Quetzal (Guatemala), the Panama Canal (partial transit), Puntarenas (Costa Rica), San Juan del Sur (Nicaragua) and Manzanillo (Mexico).
• 2019 departure: September 29.

19-day Panama Canal cruise on Princess Cruises. Round-trip from Los Angeles to Huatulco (Mexico), Puerto Chiapas (Mexico), Puerto Quetzal (Guatemala), the Panama Canal (partial transit), Puntarenas (Costa Rica), San Juan del Sur (Nicaragua) and Manzanillo (Mexico).
• 2020 departure: April 21.

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