You can explore South America on a cruise out of Los Angeles. Late in the year some ships reposition to the southern hemisphere. The long voyages take you to the wonders of the Andes and Machu Picchu, down the Pacific Coast. See the schedule of departures below.
The complete list of cruises to Brazil from the USA includes departures out of other ports.
16-night cruise to South America on Regent Seven Seas. One-way from Los Angeles to Lima (Peru). Visit Cabo San Lucas (Mexico), Acapulco (Mexico), Puerto Quetzal (Guatemala), Acajutla (El Salvador), Corinto (Nicaragua), Puntarenas (Costa Rica), Manta (Ecuador) and Salaverry (Peru).
• 2022 departure: November 3.
17-day cruise to South America on Princess Cruises. One-way from Los Angeles to Santiago (Chile). Visit Cabo San Lucas (Mexico), Puntarenas (Costa Rica), Lima (Peru), Pisco (Peru) and La Serena (Chile).
• 2022 departure: December 2.
18-day cruise to South America on Princess Cruises. One-way from Los Angeles to Santiago (Chile). Visit Puntarenas (Costa Rica), Manta (Ecuador), Lima (Peru), Pisco (Peru) and La Serena (Chile).
• 2023 departure: December 1.
16-night cruise to South America on Celebrity Cruises. One-way from Los Angeles to Valparaiso (Chile). Visit Cabo San Lucas (Mexico), Huatulco (Mexico), Puntarenas (Costa Rica), Manta (Ecuador), Lima (Peru) and Pisco (Peru).
• 2023 departure: December 7.